Programme

8.15:	Registration & coffee
8.45:	Welcome & introduction – Dr Margaret Clotworthy, Safer Medicines Trust
Session 1: Predicting human hazard
8.55:	Dr Bob Coleman – Pharmadeas: Drug Discovery and Development Tomorrow: Changing the Mindset
9.25:	Dr Paul Newbold – AstraZeneca: Humanising drug discovery to make earlier & better Stop/Go decisions in Pharma R&D
10.05:	Networking coffee
Session 2: Human tissue solutions
10.30:	Chair's opening remarks
10.35:	Prof Chris Hillier – Glasgow Caledonian University: Testing efficacy and sensitivity using small human isolated tissue
11.05:	Dr Gregory Baxter – Cornell University: Hurel, an in vivo surrogate assay platform for cell-based studies
11.35:	Prof Johannes Doehmer – BioProof: Use and value of in vitro technologies in metabolism
12.05:	Networking lunch
Session 3: In vitro & in silico solutions
1.05:	Chair’s opening remarks
1.10:	Dr Quin Wills – SimuGen: The latest technologies to 'open up' and 'read' what's going on in cells
1.40:	Prof Zvia Agur – Optimata: Virtual Patient technology to improve drug safety: A personalized medicine test case
2.10:	Prof Russell Higbee – VaxDesign: A clinical trial in a test tube
2.40:	Networking coffee
Session 4: Testing safely in volunteers
3.05:	Chair’s opening remarks
3.10	Dr Katya Tsaioun – Apredica: ADDME – Avoiding Drug Development Mistakes Early
3.40:	Prof Markus Mueller – Vienna University: Monitoring tissue drug levels by microdialysis
4.10:	Dr Mark Seymour – Xceleron: The best model for humans is human – how to accelerate early clinical development safely
4.40-5.00:	Closing remarks & Discussion

Each talk will be followed by 10 minutes for discussion